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Concomitant use of gonadotrophin releasing hormone analogues (GnRHa), which will block the endogenous feedback for monofollicular development during the low-dose step-up protocol, should not be employed.
Deregulation of endogenous feedback inhibitors of JAK/STAT signaling is well recognized in PCa and other cancers.
As IL10 suppresses the release of pro-inflammatory cytokines such as IL6 and TNFα, it is a normal endogenous feedback factor for the control of inflammation.
32 Ito et al 33 have shown that human hair follicles can synthesize cortisol, and its synthesis is regulated by endogenous feedback controls.
A recurrent theme is endogenous feedback or social interaction creating tipping points that separate multiple stable equilibria involving lower and higher levels of corruption.
Therefore, it appears that nature has utilized an endogenous feedback mechanism between MyomiRs and myosin heavy chains for fine-tuning muscle fiber type determination in order to modulate muscle physiology and performance.
Similar(54)
MicroRNAs (miRNAs) are noncoding RNAs that provide an endogenous negative feedback mechanism for translation of messenger RNA (mRNA) into protein.
OPN is unique as an endogenous negative feedback inhibitor of NO expression.
Among them are: relative deprivation as generator of hardship, generalized vanishing of the risk perception ('massive fear loss') when the uprisings surpass a certain threshold, endogenous legitimacy feedback, and network influence effects represented by the mechanism of dispositional contagion.
Similar interactions between T cells and FLSs with endogenous positive feedback loops have been demonstrated.
In addition to activating the NF-κB pathway, triggering RAGE induces de novo p65 mRNA synthesis; this results in a growing pool of transcriptionally active NF-κBp65, which appears to overwhelm endogenous autoregulatory feedback inhibitory loops [ 18].
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