As briefly discussed above, we speculate that an additional factor is required in order to produce the odd sensation; difficulty in attributing our inappropriate motor behavior to exogenous and endogenous events.
The rate of DSB occurrence in cells has been estimated at about 50 DSBs per cell per cell cycle [ 41] or ten per day [ 42], and it is increased by both exogenous agents such as chemicals, ultraviolet and ionizing radiation, and endogenous events such as arrested replication forks, nucleases and reactive oxygen species from cellular metabolism [ 30, 43].
As mentioned in Introduction, when we lose our footing (i.e. make a motor error), we are able to attribute this motor error to a self-prediction error caused by our misperception of the external world (exogenous event) or by misgeneration of the motor program (endogenous event).
Because spontaneous activity is an ongoing endogenous event that is prevailing in the brain in vivo and varies from cell to cell [66], [67], the resulting synaptic plasticity continuously occurs in the brain, being diverse at the single-cell (even single-synapse) level.
However, the percentage of recruited MSCs observed to undergo fusion (48.9%), is likely similar to endogenous fusion events, respectively.
However, although one might expect this approach to be promising for the auto-investigation of a range of sensory and motor processes, it is not yet clear whether it is adapted for the study of more endogenous mental events involving, for instance, emotional or attentional modulations.
This study investigated Sig1R and its ligands in relation to endogenous calcium events of endothelial cells and transient receptor potential (TRP) channels.
Together, these results demonstrate the ability of PA PKI to target endogenous signaling events in living cells in a light-dependent manner.
Furthermore, the disturbances in the vascular wall of neurovascular and gliovascular units also trigger vascular remodeling and angiogenesis which are considered to be endogenous adaptive events post-stroke [ 28].
To show that the role of hnRNPH and the changes in MADD and RON can be causative with respect to survival and invasiveness, we designed experiments to selectively manipulate the endogenous splicing events.
Plant serpins are likely to function in direct defence against proteinases from pests and pathogens and in the regulation of endogenous proteolytic events, but no functions have been demonstrated [ 5, 6].
