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Dr. James N. Ingle of the Mayo Clinic and a principal investigator in the study said he was surprised by the criticism over ending the study.
A front-page article on Tuesday about a study that found that Aleve, an over-the-counter painkiller, could increase heart problems misspelled the surname of a University of Washington researcher who commented on reasons for ending the study.
The most common reason for ending the study period was reaching 180 days of follow-up for women who started HAART before and after pregnancy and end of pregnancy for those who started HAART during pregnancy.
'Futility' was stated as the reason for ending the study after enrollment of 550 patients.
The main reason for ending the study was discontinuation of anti-VEGF therapy within the observation period (15.7%).
If at some point a large difference in mortality between the two treatment groups is noticed, the data safety monitoring board may recommend ending the study.
Similar(46)
The participant had the right and chance to end the study at any time.
Upon seeing that the results were already statistically solid, he ended the study for ethical reasons.
On 19 June, however, Tekmira suddenly ended the study, without fully explaining why.
In the end, the waning epidemic forced the team to end the study late last month after enrolling only 72 people.
No patients who ended the study period experienced acute rejection.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com