Lockheed Martin experienced delays during the production changes to make new external tanks with all the enhancements recommended by the Columbia Accident Investigation Board, making it impossible for them to produce two tanks for the STS-125 mission one for Atlantis, and one for Endeavour for an emergency rescue mission, if necessary in time for the original August launch date.
Had the film not been budgeted at an extravagant $90m, this could have been a profitable endeavour for all parties, but then the director is hardly known for a cost-efficient shooting style.
It has been at the forefront of European Earth science endeavours for a decade, monitoring the land, the oceans, Earth's ice cover and its atmosphere.
And it's an easy walk into the town and the beaches, and more history: it was from Whitby that Captain Cook sailed to Australia, and a tour of the harbour on a replica of his ship the Endeavour makes for a fun hour.
Guidelines on cost-effectiveness appear obvious as it is generally regarded as a desirable endeavour from a fit-for-purpose perspective.
Raising the topic of weight within a general practice consultation is a complex endeavour for GPs and practice nurses to negotiate with their patients.
Unravelling the occurrence of different cell death modes present in each AKI case, their pathological consequences and the underlying mechanisms and signalling pathways is crucial for a specific and personalized therapy and handling, and a research endeavour for the immediate future [ 137].
It demands gathering and administration of large collections of samples and related data; however, this is not an endeavour for individual biologists, single projects, or smaller research institutions, nor can it be, on account of the high costs (in time, technological resources, and funding) involved.
