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The composer Julius Harrison acknowledged the uniqueness of the work negatively: it demonstrated Stravinsky's "abhorrence of everything for which music has stood these many centuries ... all human endeavour and progress are being swept aside to make room for hideous sounds ..."....
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Thus, building on previous endeavours and progresses, EFIN made further improvement on prediction accuracy in this research area of ever increasing importance and may help move us one step closer towards accurate functional prediction of amino acid substitutions in a protein.
But true success in this endeavour, and true progress in making the world a safer place requires a deep understanding of what we're dealing with.
Empirically detecting this is a challenging endeavour, and recent years have seen progress on detecting fitness trade-offs at the scale of QTL (reviewed in Lowry 2012), including within-population QTLs (Mojica et al. 2012), though fitness effects attributed to QTLs may be confounded by linkage.
And progress is necessary.
Competence and progress count.
It represents human emotion, endeavour and impact.
The criteria reward endeavour and intent.
There was a wonderful sense of community endeavour and achievement.
I still feel proud of their courage, endeavour and contribution.
From the outset both sides fizzed with endeavour and enterprise.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com