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This type of expression pattern is representative of miRNA genes that have similar 5' end stability of the processed small RNA duplex that leads to equal incorporation of either strand into the RISC and their protection from degradation [20].
The thermodynamic properties of the miRNA-like and siRNA-like duplexes, such as terminal end stability measured through Gibbs free energy evaluation, determine the asymmetrical RISC assembly and, therefore, the efficiency of target gene silencing.
The strand with lower 5' end stability is preferred.
Additionally, the selected primer pairs had no self-complementarity, low 3' end stability and high complexity.
2) Provide stronger arguments that the asymmetry of the plate in 2 1 cells is due to differences in minus end stability.
This could be explained by similar 5' end stability of miRNA and miRNA* strands and similar incorporation efficiency into the RISC complex.
Similar(46)
Overall this suggested that in 2 1 cells, sister-kinetochores form amphitelic microtubule attachments, but that differences in minus-end stability delay stabilization of kinetochore microtubule attachments in both half-spindles, as reflected by higher levels of SKAP-negative kinetochores.
Whoever ends up in government will be pursuing small "c" conservative ends: stability and security.
The driver needs good rear-end stability for braking and turning into Turn Six and then he needs to get on the accelerator as quickly as possible to accelerate towards the 130mph right-left kink at Turns Eight and Nine and then the long, long double apex right-hander at Turns 10 and 11.
The cross-strait telecom pact signed on Monday also included cooperation on technical research to enhance the China 3G networks end-to-end stability; on market research to study Chinese consumers and to explore psychological factors that can influence Chinese users product awareness, attitudes, usage habits and behavioral motivation.
Moscow sent troops, the violence ended, stability returned.
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