Sentence examples for end resection needs from inspiring English sources

(5) The A-NHEJ process, initiated by MRN- and CtIP-dependent DSB end resection, needs the ERCC1 XPF nuclease and DNA ligase I/III XRCC1 complex, but is independent of the DNA-PKcs, DNA ligase IV, or Ku complex.

Thus, targeting of NuA4 does not require DNA end resection per se but needs it to spread to neighboring regions.

MRX is thought to act in concert with Sae2 with respect to DNA end resection.

This finding suggests that Cdk1-dependent phosphorylation events might simply potentiate the resection machinery by promoting the removal of negative regulators of DNA end resection.

HR is initiated by 5′ to 3′ end resection.

However, BRCA1 somehow associates with initiation of DSB end resection.

GamGFP inhibits IR-induced RAD51 foci, apparently blocking end resection.

CtIP promotes DSB end resection in HR and A-NHEJ.

(22) The BRCA1-C compromotesmotes DSB end resection.

SIRT6 also promotes DNA end resection by deacetylating CtIP (CtBP-interacting protein), a protein involved in DNA end resection.

It also plays a role in DNA repair by homologous recombination, possibly by promoting end resection.