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After determination of saturation and relative permeability end point values, relative permeability curvatures in mathematical function can be adjusted until the flow behavior match the laboratory observations.
To this end, point values are assigned so as to encourage students—in the face of uncertainty to use intermediary points along the lines connecting the vertices of the triangle.
Data are presented as median (lower and upper quartile) for end point values.
After an adjustment for multiple comparisons (α′ = 0.017), the difference between G1 and G2 end point values was no longer statistically significant; however, the difference between G1 and G3 remained significant.
In animal xenograft models, the log-rank test was used to determine the statistical significance of the difference between the time to end point values of two groups, except any (non-treatment-related) deaths.
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Median survival of animals treated with PBS was 36 days (95% CL = 26 days to 42 days) at which time the Fluc end point value of 109 photons/sec/cm2/steradian was reached (approximately one week before the onset of neurological symptoms).
Measures of insulin dose and body weight were analyzed as the end point value using last observation carried forward for each patient.
An alternative end point value could be 17.3, which is the isotope ratio for two subjects with PbB < 2 μg/dL (the left end of the Esperance ellipse in Figure 2).
According to the Last Observation Carried Forward approach, 12 the last observed value of the mNAPSI score was used as an end point value in the event that patients prematurely withdrew from the study (for any reason).
Assuming that the low-Magellan end point value is valid, it would appear that the PbB of all the children analyzed for Pb isotopes contains a proportion of Magellan Pb.
These biomarkers could be validated using outcome information we collect across the triple aim, emphasizing end points valued by patients and families while accounting for important patient and environmental characteristics.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com