Sentence examples for end point in the development of from inspiring English sources

We evaluated animal and human toxicity data for perchlorate and identified reduction of thyroidal iodide uptake as the critical end point in the development of a health-protective drinking water level [also known as the public health goal (PHG)] for the chemical.

However, in study 1 cattle were culled at a predetermined time point post challenge or, in both studies, at a predetermined end point when the development of BSE was not expected in surviving animals.

To evaluate the validity of using progressive loss of neuroretinal rim area as a surrogate end point for the development of visual field loss in glaucoma.

The primary end point was the development of diabetes defined as hospitalization with a diagnosis of type 2 diabetes.

The primary end point was the development of type 2 diabetes, the duration of follow-up was 3.2 years.

Systemic recurrence-free survival analysis was performed with the end point being the development of systemic disease.

The cohort was followed initially for 6 years with the end point being the development of type 2 diabetes.

The primary end point was the development of persistent microalbuminuria (overnight albumin excretion, ≥20 μg/min at two consecutive visits).

The primary end points were the development of microalbuminuria, macroalbuminuria, end-stage renal failure, or induction of hemodialysis.

Thus, from the point of view of circuit formation, we have a relatively good understanding of the end point in cerebellar development, making the cerebellum a good model system for circuit development.

The development of biomarker strategies could be part of a movement toward more ecologic end points in the safety evaluation of chemicals, which would effect a reduction in animal tests that cause suffering.