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For the specific clinical end point, compliance and QOL univariable and multivariable Cox proportional hazard regression models will be used to calculate HRs with 95% CI among the stages of disease at baseline.
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18 23 Additional end points included compliance with mask use, defined as using the mask during the shift for 70% or more of work shift hours.
The same authors made the final selection; we restricted the selection to articles that reported on relevant study end points, including pulmonary compliance, arterial oxygenation, sputum clearance, duration of mechanical ventilation, length of stay in the intensive care unit, and incidence of pneumonia, and only if the main objective concerned the evaluation of the MH procedure.
Accordingly, it is important, even within a risk-management framework that risk-management be translated into rule-compliance for end point decision-makers, where possible.
Body weight loss > 20% was the end point for termination from the study in compliance with IACUC guidelines.
As compliance with end of life wishes was the primary end point of this study, only patients aged 80 or more were enrolled, as this age group is responsible for 51% of the deaths at our hospital.
Acceptable progress toward compliance criteria is best measured by trends approaching a desired end point.
13 Thirdly, we needed to make assumptions that compliance with scheduled clinic visits was independent of the risk of the end point to justify our statistical approach.
The primary end point of interest was the mean rate of adverse events in the two study arms, including decreased compliance.
The end point is July 31 , 2008
Note, no end point is achieved.
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