Sentence examples for end of the mutation from inspiring English sources

TP53 is mutated at the end of the mutation pathway, and many cancer cells without a mutation in this gene can be observed within the specimen [ 22- 25].

On the other end of the mutation spectrum is the simple M680I heterozygosity found in one of the healthy volunteers, C6b, which did not result in any clinical or subclinical (cytokine profile) FMF manifestation.

Significant bias occurs primarily at the upper end of the mutation rate distribution, where the infinite sites model of at most one mutation per site breaks down and sites may be subject to multiple mutations.

At the mild end of the spectrum, mutations in GMPPB lead to the limb-girdle muscular dystrophy that is limited to a weakness in the proximal limb muscles.

At the severe end of the spectrum, mutations in GMPPB lead to the congenital muscular dystrophy with brain and eye abnormalities.

Whereas a loss-of-function mutation in TLR results in increased susceptibility to infections [ 42], at the opposite end of the spectrum, productive mutations in TLR might result in increased receptor avidity for otherwise low-affinity foreign or even unrelated self TLR ligands.

At the other end of the spectrum, advantageous mutations are of small effect, and land in numerous clonal lines.

Near the end of each Mutation record, you will find a list of the strains we have that carry that mutation, and you can examine each of those.

Both fragments contain a 30 50 bp region designated HR3 at the 3'-end of the 5'-mutation fragment and at the 5'-end of the 3'-mutation fragment.

Changing musical styles at the end of the 16th century made mutation necessary too often to be practical.

On the other end of the spectrum, a genetic mutation in some Swedish families leads to early onset of severe Alzheimer's disease, high levels of protofibrils but no plaque.