Sentence examples for end of replication from inspiring English sources

In E. coli, DnaB helicase plays a central role; which displays protein-protein interactions right from the beginning to the end of replication process.

Gyrase is unique in introducing negative supercoils into DNA, whereas topoisomerase IV primary function is decatenation of DNA at the end of replication [ 7].

In E. coli, two supplementary topoisomerases are involved in the decatenation process, allowing for chromosome separation at the end of replication.

In budding yeast, the F-box protein Dia2 drives ubiquitylation of the CMG helicase at the end of replication, leading to a disassembly pathway that requires the Cdc48 segregase [ 3].

A characteristic of these viruses is the presence of two different phenotypes during virus infection: budded virus (BVs) in the initial part of multiplication cycle and occlusion bodies (OBs) at the end of replication [ 1, 2].

Topoisomerase II (TOP2A) is a nuclear enzyme that modulates DNA topology during several metabolic processes and is required for the segregation of daughter chromosomes at the end of replication [ 48].

However, HIT-Seq reveals that Integrator also binds to the 3′ end of replication-dependent histones and promoter proximal regions of genes with polyadenylated transcripts.

Integrator binds to the 3′ end of replication-dependent histone genes, and this binding was confirmed via ChIP at a Histone H2A gene.

Therefore, it is likely that DSIF and NELF are functionally coupled at all loci, including the 3′ end of snRNA genes, the 3′ end of replication-dependent histone genes, and the promoter proximal regions of genes with polyadenylated messages.

Beyond the snRNA loci, we show that Integrator binds to the 3′ end of replication-dependent histone genes and promoter proximal sites in a subset of genes that produce polyadenylated transcripts.

LEDGF IBD fusions to each member of the NELF complex and SPT5 were also constructed (Supplementary information, Figure S1H) for use as control markers for binding to the 3′ end of snRNA genes, 3′ end of replication-dependent histone genes, and promoter proximal regions of genes with polyadenylated messages.