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In contrast, Ray Kurzweil, Google's chief engineer, depicts a technological utopia bringing about the end of disease, poverty and resource scarcity.
Although such studies are ideal for estimating the duration of disease they are less suitable for estimating the CF. In order to obtain an estimate of the CF one needs either follow-up of incident cases or estimates of the frequency with which disease ends in death among those patients for whom the end of disease is observed.
All experimental procedures were reviewed and approved by the Ethical Committee for Animal Experiments of the VU University Medical Center (Amsterdam, The Netherlands) Four animals per group were sacrificed for T cell proliferation and histological examination on the peak of disease (day 15) and at the end of disease (day 29).
Moreover, the surviving animals showed skin lesions and scabs toward the end of disease evolution.
At the opposite end of disease spectrum, there have been significant shifts in the treatment of patients with advanced RCC.
The three general neurology clinic neurologists, for example, indicated they could envision a palliative care approach for MS patients once they were no longer being treated with immunosuppressive or immunomodulatory medicines (subcategory end of disease modification).
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Lithium was administered starting at 67 days of age until the end point of disease.
Existent biomechanical studies on hip osteoarthritic gait have primarily focused on the end stage of disease.
The end mediators of disease appear to be the reactive intermediates produced by both inflammatory cells and intrinsic glomerular cells.
It follows that pathway activity should also be affected, with a potential end result of disease [ 8- 10] or lethality.
Therefore, mortality is appropriate to define the end result of disease progression; however, it is not appropriate for describing disease progression in individual patients or in clinical practice.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com