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Metabolic Control Theory [ 26] has demonstrated that tighter control of pathway fluxes can be maintained by regulation of demand than supply, i.e. near the end of a pathway.
Using a coarse grained Elastic Net Model, we show that the binding site lies at the end of a pathway of evolutionarily conserved residues in RyR2.
This is necessary to avoid a build-up of tokens at the end of a pathway as this would lead to biased results for nodes that have zero out-degree (i.e. nodes from which no other node can be reached).
You can position a gazebo,an arbor or fountain at the end of a pathway.
Similar(56)
In the case of wild-type p62 and concentrated LC3B, the interaction even becomes irreversible and might represent the end point of a pathway in which the whole structure is eventually degraded in the lysosome.
By Margaret Talbot Roald Dahl, the British author of children's books, wrote in a tiny cottage at the end of a trellised pathway canopied with twisting linden trees.
Through the front door off Park Avenue, a windowless wooden door at the end of a brick pathway, you enter the 18th century, when Job Sammis, a weaver, lived in this red-shingled cottage with his family.
Roald Dahl, the British author of children's books, wrote in a tiny cottage at the end of a trellised pathway canopied with twisting linden trees.
Genes which receive signals from many parallel paths exhibit normal statistics while genes which lie at the end of a single pathway are prone to large statistical variations and highly skew statistics.
Methods, which predict the localization at the end of a complex pathway, are less reliable when applied directly to sequences.
Biochemical reactions transform chemical graphs into compatible chemical graphs and, therefore, the origin and the end of a metabolic pathway will be compatible sets of metabolites.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com