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It is exhausting, disorienting, and, in the end, depressing.
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In the end, depressed and exhausted by men's harassment, they both commit suicide.
Otherwise you might end up depressing him or her further.
This ends up depressing her to the point where Marge starts drinking a glass of wine to cope with her depression.
In the end, though, depressed Charlie can't allow himself even the wispy hope represented by his chuckleheaded doppleganger.
That may well be a positive factor in the long term but will likely lead the banks to sell more of their stock holdings before the fiscal year ends next March, depressing the market.
Here's another, which starts with a job interview and ends with a depressing reminder of our own frail mortality.
We end our roundup of depressing news with the students in the weird, French part of Canada who've turned on the authorities for their plans to hike college tuition fees by $1,600.
When we look back, we see random paths that rambled off to the side, odd little side trips and depressing dead ends, all of which seem irrelevant to the BIG story we present to ourselves and to the world.
Since this is the only thing coming from Black Mirror in 2018 that we know of, it stands to reason that we'll be picking our own depressing Bandersnatch ending or whatever.
Plungers at the other end are then depressed in sequence to release reagents.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com