Exact(2)
These mRNAs typically harbor lengthy, G+C rich, highly-structured 5' UTRs that encumber efficient RNA unwinding by the eIF4F complex and subsequently prevent efficient ribosome loading [14].
AAV2's higher HSPG affinity, but lower transduction efficiency, relative to ShH10's (Fig. S2) may then suggest a potential dueling role in achieving optimum transduction, as too high of an affinity may also encumber efficient viral penetration in the retina.
Similar(55)
In tough market climates, small-company stocks can tend to outperform larger, more encumbered businesses thanks to better (i.e., more efficient and effective) margins and management as well as the loyalty of the consumer base.
Though viral carriers are undeniably the most efficient for gene delivery, their use is encumbered by potential safety issues such as pathogenicity and immunogenicity.
"So we encumber their own art".
And efficient.
More efficient?
Efficient servers.
Ruthlessly efficient.
Efficient, that.
Terribly efficient.
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