As a forthcoming Bright Blue report will outline in detail, the self-employed now encounter major challenges around financial resilience and being able to operate on a fair and level playing field.
Research to achieve these outcomes continues to encounter major challenges; however recent developments have reiterated the potential of chromosome-based vectors for therapeutic gene delivery.
However, the resources required to drive the 'quality agenda' and the sustainability of quality interventions have encountered major challenges [ 2].
The evaluation encountered major challenges in terms of balancing data between two phases (child welfare under MoES and child care under MoLHSA) of the reporting period.
Yet, they encounter major challenges such as commercialisation of the university's and medical school's central purpose, perceived lack of accountability of higher education and heightened sensitivity of taxpayers towards ineffective and inefficient leadership in academia.
However, several recent reports show that because of tumor heterogeneity and the fact CTCs frequently lose their epithelial nature upon epithelial mesenchymal transition (EMT), the detection and enrichment of CTCs based on EpCAM often encounter major challenges.
MS is considered a T-cell-mediated disease, but until now the study of pathogenic T cells has encountered major challenges, most importantly the limited access of brain-infiltrating T cells.
However, the detection and enrichment of CTCs based on a single cancer cell marker, most commonly EpCAM, often encounter major challenges because of the phenotypic heterogeneity among CTCs and their biological plasticity during the metastatic process, known as the epithelial-mesenchymal-transition (EMT).
Scale up of visual inspection with acetic acid (VIA) in Guatemala encountered major challenges, including high attrition of people trained, didactic training without hands-on skills building, lack of continued supervision, and provision of VIA alone without immediate on-site provision of cryotherapy.
"United Nations peacekeeping is encountering major ethical and practical challenges".
