Sentence examples for encounter damage from inspiring English sources

Again it is optimal for the replicative system to expect to encounter damage.

A polymerase is more likely to encounter damage somewhere in the replication of these large genomes than a prokaryote with a smaller genome in a similar environment.

Most of these patients encounter damaged stomatognathic system or facial deformity, which result in serious physiological and psychological disorders [ 10].

When replication forks encounter damaged DNA bases, crosslinks or tightly bound proteins, they can stall irreversibly (Dimitrova & Gilbert, 2000; Tercero & Diffley, 2001; Merrick et al, 2004).

The multi-protein inflammasome complex, comprising the NLRP3 polypeptide, ASC or PYCARD (apoptosis-associated speck-like protein containing a CARD) and caspase-1 [ 12] forms when monocytes and macrophages encounter damaged and pathogen-associated molecular pattern proteins (DAMPs and PAMP; e.g., bacterial lipopolysaccharide or MSU crystals) and leads to activation of caspase-1.

Therefore, it is likely that the DNA replication machinery frequently encounters damaged templates giving rise to stalled replication forks.

A second negative consequence of having large inter-origin gaps arises from problems that occur if replication forks irreversibly stall, for example, after encountering damaged or chemically modified DNA [57].

During the second labelling period we damaged the DNA such that the advancing fork will encounter DNA damage and may stall (Fig. 4A).

"Even if you win the encounter, the damage you sustain will be far greater because it hurts your reputation and career longevity," he writes.

When proliferating cells encounter DNA damage, they must pause cell cycle progression in order to allow repair of the lesion(s), if possible [21].

Forks can stall if they encounter DNA damage.