Despite this commonness of the HCR diagnosis, we encountered ambiguity among physicians regarding the definition, etiology, and management of HCR.
This was clearly very uncomfortable for many students, who generally have not encountered ambiguity in quantitative exercise results before.
As the gap size increases, so does the likelihood of encountering ambiguity, making it more difficult to fill gaps for longer fragments.
We used the recommended meme method in our analyses, setting the options to estimate the global dN/dS value and to average encountered ambiguities in the consensus sequence (Murrell et al. 2012).
Kenyon et al. (5 ) also encountered diagnostic ambiguity in invasive fungal infection cases: over an 8-year period in South Africa, 39 cases were diagnosed as histoplasmosis on the basis of histologic findings, and only 1 was confirmed by using molecular techniques.
* * * In 1966, the University of Toronto psychologist Daniel Berlyne proposed that curiosity arises when we encounter uncertainty or ambiguity in our environment, whether it's physical (a place or an object we haven't seen before) or mental (a word we don't know, a question we can't answer).
* * *In 1966, the University of Toronto psychologist Daniel Berlyne proposed that curiosity arises when we encounter uncertainty or ambiguity in our environment, whether it's physical (a place or an object we haven't seen before) or mental (a word we don't know, a question we can't answer).
The ambiguity encountered with CORE was almost entirely accounted for by sequences assigned to the Streptococci, which show low inter-species variation in the 16S and so are incompletely resolved with short sequences.
Thus, the ambiguity encountered when these organisms are identified by MALDI-TOF is not surprising.
The amplitude-contrast images were obtained by calculating the intensity distribution as follows: (3) I m, n = Re E x, y ; z 2 + Im E x, y ; z 2 and the phase-contrast image was derived from the following argument values: (4) ϕ m, n = arctan Im E x, y ; z Re E x, yl ; z The 2π ambiguity encountered in the wrapped phase image was resolved by the unwrapping process [ 72].
