The proposed integrated disaster governance, management, and coordination frameworks have the potential to shift the focus of disaster policy and management in Brunei from overreliance on disaster response, to primarily encompass prediction, prevention, and mitigation.
Ranking predictions according to precursor similarity resulted in 857 groups encompassing 4,060 predictions (2,233 of which also belonging to position groups): in total, 2,575 similarity groups were obtained (857 groups + 1,718 ungrouped precursors).
780 groups encompassing 2,228 predictions were obtained, while 3,550 precursors remained ungrouped.
The GrapeMiRNA database encompasses 5,778 microRNA predictions spanning the whole grape genome.
As noted in previous work, B-cell epitope prediction encompasses diverse phenomena ranging from mechanistically very simple cases (e.g., antibody-mediated enzyme inhibition in vitro) to high-level biological processes (e.g., of antibody-mediated immunity to infection) [ 9].
However the prediction itself encompasses a difficult optimization problem with thousands of degrees of freedom and is associated with extremely complex energy landscapes.
Risk assessment of micropollutants encompasses three dimensions: (i) prediction of toxicity under long-term and fluctuating exposure, (ii) extrapolation from lethal to sublethal end points and (iii) extrapolation from one (or a few) tested species to many (all) species in the water body of concern.
The median model predictions were within 0.2 to 3.6 fold of the measured median, and the 95% CIs of model predictions encompassed all the measured medians at each sampling time.
Importantly, our predictions encompass both intracellular and extracellular metabolites.
Thus, the selected predictions encompass 3,616 different putative targets (864 + 2,752).
