In hindsight, the overall fold similarity to a domain is a necessary condition for inferring its biological function since the ideal notion of protein domain necessarily encompasses an unit of function by definition.
Functionally, the lncRNA class encompasses a wide variety of distinct functions like X-chromosome inactivation, modulation of chromatin structure, regulation of transcriptional and posttranscriptional processes and epigenetic modifications (14).
The purpose of this division is to acknowledge that stage 3 CKD encompasses a broad range of renal function and that there may be clear biological distinctions among the renal bone vascular calcification pathophysiology (e.g. CKD MBD) between 3A and 3B CKD.
While 'dementia' in current neurological settings is typically used to describe a progressive disease of the brain, it perhaps more accurately encompasses a deterioration of intellectual or cognitive function that may or may not be progressive in nature [ 70].
This set of copy number variable genes encompasses a wide spectrum of molecular functions, biological processes, pathways, cellular components and Panther protein classes.
Sleep is vital to all human functioning and encompasses a complex set of physiological and behavioral processes; disruption in one or more of these processes can lead to many different types of symptoms of poor sleep that can occur singly or in combination.
The function of these genes encompasses a spectrum of cellular activities including cell cycle control and the response to DNA damage.
DOI: http://dx.doi.org/10.7554/eLife.09224.002 The ASCE [Additional Strand Conserved E (glutamate)] division of oligomeric, ring-shaped NTPases encompasses a diverse range of enzymes that function as molecular motors (Lyubimov et al., 2011).
These results suggest that this small 90 amino acid region, called the AP2 Activator motif (APA), encompasses a large fraction of FCHO-1 function in vivo.
Synaptic plasticity encompasses a great variety of changes in synaptic function and structure.
