Sentence examples for encoding gr from inspiring English sources

Nr3c1, encoding GR itself, was repressed, though Nr3c2 (encoding MR) was unaffected by dexamethasone.

To examine this possibility, comprehensive silencing of genes encoding GR and proteoglycan core proteins was conducted in Drosophila.

Polymorphisms in the human Nr3c1 gene (encoding GR; here abbreviated to GR) are associated with hyper- or hyposensitivity to exogenous glucocorticoid (dexamethasone) suppression of the hypothalamic-pituitary-adrenal (HPA) axis and a range of metabolic and cardiovascular parameters.

To test whether having at least one of the two major cytosolic NADPH-dependent disulfide reductases was essential for hepatocyte homoeostasis in vivo, our group ablated the Txnrd1 gene, encoding TrxR1 [ 32], in the hepatocytes of mice homozygous for a germline disruption of the Gsr gene, encoding GR [ 27].

Through trial-and-error we have injected 0.2 ng of mRNA encoding GR-nuc-GFP for each frog embryo.

Capped mRNA encoding GR-nuc-GFP was synthesized and purified using standard methods from a linearized DNA template (AmpliCap Transcription kit; Epicentre Biotechnologies, Madison WI).

However, in situ mRNA hybridization histochemistry of GR mRNA, using a probe complementary to exons 5 9 of GR (absent from mRNA encoding GR-βgeo; Fig. 1 A ) showed a halving in the full-length GR mRNA levels in the brain (hippocampus and paraventricular nucleus of the hypothalamus) and pituitary of GRβ geo /+ mice compared with GR+/+ littermates (Fig. 2 B – D ; Table 1).

To isolate cDNA sequences encoding GRs from Pantodon buchholzi and Acipenser ruthenus, amino acid sequences of the highly conserved E-domain of a number of vertebrate GRs were aligned and degenerate primers derived (see Materials and Methods).

A polymorphism within the DNA binding domain of the pSV2wrec-encoded GR (encoding Val437) (33) was changed to Gly437, to be identical to the C57BL/6J and 129 mouse strain-encoded GR, by site-directed mutagenesis.

We co-injected RNA encoding Mix-GR-HA into ventral vegetal blastomeres with mini-Ruby (Fig. 6F), and then isolated embryos that had been properly targeted.

To do this, mRNAs encoding GILZ, GR- α and Bim were measured by quantitative RT-PCR after 6 h and 22 h incubation with or without dexamethasone.