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As shown in Figure 2, in the upper level of our encapsulated software, GRAM encapsulates another layer, namely, the GRAM component internal service layer.
Our encapsulated software is stored in the master node.
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Moreover, MAS is designed to encapsulate software parts in agents that can be maintained or exchanged independently and easily.
The concept of aspect orientation has been around since 1978 as an additional way of structuring and encapsulating software.
In object-oriented programming (OOP) languages, the ability to encapsulate software concerns of the dominant decomposition in objects is the key to reaching high modularity and loss of complexity in large scale designs.
Secondly, we embed the encapsulated bioinformatics software in the compiled GRAM service [ 9]; GRAM called this application and provided bioinformatics software's service to the outside [ 10].
After encapsulating bioinformatics software, we should publish it next.
Firstly, we further encapsulate the software with a GRAM service provided by Globus.
In addition, the paper explains the algorithms, which are encapsulated in the software.
This is a feature implemented in the QuBiLS-MAS software encapsulated into a batch processing module, which is useful for carrying out high-throughput and routine MD calculations.
To validate the reproducibility and feasibility of our framework, the authors encapsulated the entire software development environment as a VirtualBox [33] image file, and asked several volunteers at different countries s around the world, such as Singapore, Romania, Australia, England, and USA, to run these experiments.
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