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Exact(3)
mathrm{EE} left(%right)={C}_f/{C}_itimes 100 (1)where C f is the encapsulated amount of ERL or DOX in the nanoliposomes measured after destruction of the nanoliposomes with 10% Triton-X 100 for a complete release of ERL or DOX from them.
The increasing DS value led to a decrease in the encapsulated amount due to the decrease in the hydrophilic core space, while the low DS value (less than ca. 20 mol%) led to a destabilization as a unimolecular nanocapsule and a lower encapsulation ability.
The encapsulated amount of DOX or Gd-DTPA was calculated by subtracting the DOX or Gd-DTPA residue from the initially added amount of DOX or Gd-DTPA.
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Absorbance was converted to amount of drug using a standard graph and the encapsulation efficiency was calculated using the following: (1) Encapsulation Efficiency = Drug encapsulated Total Drug × 100.
> -wrap-foot> aRelatod thetotalotamountunt of monomers The maximum encapsulated PMI amount corresponds to the introduced amount of PMI, i.e., 0.5 mg PMI per 1 g of the polymer.
It is likely that hydrophobic cavities of β-CD also encapsulated some amount of drug along with its inner core which could enhance the drug loading capacity of these NPs.
Being a highly hydrophilic drug molecule, it is very difficult to encapsulate high amount of 5-FU within the hydrophilic polymer matrix.
The lack of dependence on indium concentration is logical since there is always a large excess of tropolone and polymer in the studied range, which allows encapsulating sufficient amount of activity at radiolabeling efficiency of 30%%.
Thus, encapsulating small amount of such immunostimulatory adjuvant into biological inert vehicle of PELC is a probable strategy to improve the innocuity of vaccines.
Encapsulating higher amount of AmB in cholesterol containing liposomes may result in leakage of AmB from the liposomes to the human tissues and organs.
Upon increasing the encapsulation temperature to 100°C, the amount encapsulated increased to 161 μmol/g (2 h of encapsulation).
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