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Interestingly, the teeth appeared to develop normally until the secretory stage of enamel development.
Is resin infiltration an effective esthetic treatment for enamel development defects and white spot lesions?
Matrix metalloproteinases play an important role during the initial process of enamel development and therefore may play a role in caries.
This study analysed prenatal and postnatal enamel development and postnatal calcification in upper second primary molars from FD children in comparison with healthy controls.
So far, the recombinant porcine, mouse and bovine MMP-20 have been cloned and used extensively in the researches of tooth enamel development.
While the role of these proteins is not fully understood yet, it is believed that both classes of proteins aid in the enamel development by serving as a framework support (Avery 2001; Nanci 2012; Margolis et al. 2006).
To complicate the process even further, regular and discrete domains of various charges or charge densities on the surface of apatite crystals derived from the maturation stage of enamel development were discovered by a combination of atomic and chemical force microscopy (Kirkham et al. 2000).
By exposing undifferentiated cells to a self-assembling matrix bearing RGDS epitopes, we elicited a regenerative signal at will that subsequently led to the identification of thrombospondin 2 (TSP2), an extracellular matrix protein that has not been previously recognized as a key player in enamel development and regeneration.
Dental enamel development occurs in stages.
Amelogenin is the most abundant EMP during enamel development [7].
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Systematic reviews of previous studies found a lack of reliable evidence on a protocol or a method to protect the enamel against development of white spot lesions during orthodontic treatment or to remineralize post-orthodontic white spot lesions [23, 24].
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