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This is because, in principles, distinct binding sites of a protein are not necessarily coupled, thereby enabling them to evolve somewhat independently and to eventually lead, after gene duplication, to a partition of the most conserved binding site copies between each protein duplicates (i.e. this amounts to a "subfunctionalization" between duplicated genes, see additional file 1).
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We can hypothesize, that tumor cells are characterized by particular pattern of activated transcription factors, which enabled them to evolve from pre-tumor to tumor state by escaping multiple checkpoints and by establishing signal independent uncontrolled proliferation.
domingiensis resource may thus confer a selective advantage to parasitoids that are able to counter the host resistance, which may then enable them to evolve as a specialist entity.
The nervous systems of poikilothermic animals must have evolved mechanisms enabling them to retain their functionality under varying temperatures.
They thrive in agricultural ecosystems because they have evolved traits enabling them to withstand crop competition and cultural practices, including herbicide applications, aimed at disrupting their demography [ 2, 3].
Diverse bacterial species have evolved unique structural adaptations enabling them to migrate in their environmental niche.
Some yeasts have evolved a methylotrophic lifestyle enabling them to utilize the single carbon compound methanol as a carbon and energy source.
The pattern of brain variation seen in both humans and chimpanzees suggests this structural variation evolved in a common ancestor, enabling them to adapt to selective pressures in their environment.
Innovations such as this require freedom to evolve and enable them to 'happen'.
Humans have evolved mechanisms that enable them to cooperate with genetic strangers on the basis of reciprocity.
Forest ecosystems are fire-maintained, having evolved traits that enable them to persist with, and depend upon a variety of fire regimes.
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