Sentence examples for enabling the enzyme from inspiring English sources

cdMMP7 was over-expressed in an E. coli over-expression system, and the resulting enzyme was processed into inclusion bodies, which were subsequently solubilized, enabling the enzyme to be re-folded into a catalytically-active form.

Shown to work just 3 years ago, CRISPR consists of a an enzyme called a nuclease and a piece of RNA that homes in on a targeted DNA sequence, enabling the enzyme to introduce precisely targeted mutations, corrections to mutations, or other alterations.

These structures explained, among other phenomena, the active-site promiscuity in terms of spermidine binding, enabling the enzyme to synthesize spermine [ 124, 125].

Despite this, eNOS is often tonically active in blood vessels, perhaps the most important mechanism for sustaining the activity being phosphorylation on serine-1179, enabling the enzyme to function at resting cytosolic Ca2+ concentrations.

Flavivirus helicases possess nucleoside triphosphatase activity, which enables the enzyme to convert chemical energy to unwind viral RNA replication intermediates.

Longer pRNAs (approx. ≥ 10 nt) rearrange the 6S RNA structure and thereby disrupt the 6S RNA RNAP complex, which enables the enzyme to resume transcription at DNA promoters.

Specific modification of individual cysteine residues in U-binding pocket — targets introduced into certain positions by site-directed mutagenesis — enables the enzyme to effectively replicate DNA containing uracils.

We subsequently refined the structure of the substrate-binding model by means of energy minimization, indicating that slight movements of residues I167, N173 and F212 enable the enzyme to adapt to 3-quinuclidinone (Figure 4c).

Assembly of zinc finger DNA-binding domain to a DNA-cleavage domain enables the enzyme machinery to target unique locus in the genome and invoke endogenous DNA repair mechanisms.

The large equilibrium dissociation constant can be translated to a fast off-rate (Xing et al. 2014), which would enable the enzyme to rapidly scan through potential methylation sites, and account for the high abundance of m6A modification in coding and non-coding RNAs (Dominissini et al. 2012; Sun et al. 2016).

As a result, the substrate does not simply bind to a rigid active site; the amino acid side-chains that make up the active site are molded into the precise positions that enable the enzyme to perform its catalytic function.