Sentence examples for enabling the activation of from inspiring English sources
Upon apoptosis induction, IAP proteins are antagonized by their endogenous inhibitor Smac (second mitochondria-derived activator of caspase), which is released from the mitochondrial intermembrane space, enabling the activation of caspases.
Altogether, our data demonstrate that zVAD-fmk cannot potently prevent caspase-10 processing in Fas signalling, enabling the activation of a caspase-10-dependent alternative cytotoxic signalling pathway in response to FasL.
Signaling complexity is increased further by receptor promiscuity, enabling the activation of different G proteins by the same receptor subtype.
The construct includes an enterokinase site, enabling the activation of GrB and an IGκ leader sequence for secretory expression.
Engagement of PKC with the membrane leads to a conformational change and full activation of PKC, enabling the activation of PKC-mediated downstream signalling events.
Components of the erythrocyte membrane facilitate coagulation and the loss of the filtering function of the spleen allows abnormal red blood cells to remain in the peripheral circulation, enabling the activation of the coagulation cascade, especially in chronic hemolysis [ 110].
Based on the enzymatic etching of CdS QDs enables the activation of quenching the charge transfer efficiency, thus leading to sensitive PEC recording of H2O2 level in buffer and cellular environments.
Density Functional Theory simulations conducted on In2O3(1 1 1), which was experimentally and theoretically shown to be the most exposed surface termination, indicated that oxygen vacancies surrounded by three indium atoms enable the activation of CO2 and split hydrogen heterolytically, stabilizing the polarized species formed.
This may then enable the activation of the adaptive immune system against tumour cell products (Adams and Weiner, 2005; Carter, 2006).
In GBM, the interplay between alternative RTK pathways can be exploited by tumor cells to enable the activation of oncogenes in the face of EGFR inhibition [ 42].
