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These proteins play a central role in enabling T cells to respond to foreign substances.
The adhesion molecules corresponding to these receptors were found to be constitutively expressed in islets, enabling T cells bearing these receptors to infiltrate the islets and to cause diabetes.
A rapidly expanding understanding of molecular and cellular events that contribute to a reduction in numbers and/or activation of intra-tumor T cells has facilitated the development of gene-engineering strategies, enabling T cells to counter immune tolerance.
However, the error performance of R B may still be unsatisfactory due to additional constraints imposed at R A. It is noted that this effect is particularly apparent when T B is located physically close to R A. The overlay CR model is designed to overcome the poor error performance at R B by enabling T B to help U A relay its signal while concurrently transmitting its own signal.
SDF28z exhibited greater functional activity, enabling T cells to kill T47D tumour cells.
The TCR trans-membrane molecule consists of an antigen-specific αβ heterodimer receptor coupled to invariant γδϵ and ζ homodimer chains that mediate signal transduction - enabling T cell proliferation and cytokine secretion.
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Finally, XTENylation drastically improved the solubility of the T-20 conjugates, enabling T-20-XTEN to be formulated at high concentrations without any indications of aggregation.
Both subsets express ligands enabling T-cell extravasation and tumour infiltration (Ohmichi et al, 2011; West et al, 2013), possibly potentiating immune cell infiltration synergistically.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com