Sentence examples for enabling specificity from inspiring English sources

Fingers with different triplet specificity can be engineered by mutating the key amino acid residues hence enabling specificity in DNA recognition by ensuring a large number of combinatorial possibilities.

A composite element contains two functionally linked binding sites for distinct transcription factors and in this way provides the basis for integrating the inputs of two signaling pathways and enabling specificity of expression [ 38].

In recent years, it has become clear that plant defense responses are complex, and that they arise from crosstalk between different hormonal signaling pathways that enable specificity of responses to different pathogens and fine-tuning of defense responses [ 5, 9].

Characterization of the docking hits in in vitro assays reveal two potent, Sirt2-specific compounds as well as a target site apparently enabling isoform specificity and additional compound scaffolds for further development, demonstrating the power of this approach for the development of specific Sirtuin inhibitors.

Structure comparison and the predicted, shared binding mode of the Sirt2-specific compounds indicate a pocket extending from the peptide-binding groove as target side enabling isoform specificity.

Twenty-three articles (23/78; 29%; 95% CI 20%to41%1%) presented Receiver Operating Characteristic (ROC) curves, yet only four articles labelled the curve at specific points enabling sensitivity and specificity to be read off at these points.

In addition, compared with the linear chain probes, the molecular beacons probes enabled higher specificity and wash-free operation.

The development of such strategies that achieve tumour targeted expression of genes via selective promoters will enable improved specificity and targeting thereby addressing one of the major limitations of cancer gene therapy.

Our experiments demonstrated that this more cost-efficient method enables high specificity, sensitive detection of miRNAs in S. japonicum.

Incubate the beads with APex Heat-Labile Alkaline Phosphatase (Epicentre) to remove phosphate group, which enables strand specificity at the later PCR step since only the bottom strand cDNA can be ligated and thus amplified.

In A. thaliana, RPM1 gene enables dual specificity resistance to two avirulence products (AvrRpm1 or AvrB type III effector protein) of Pseudomonas syringae, a causal agent of bacterial blight disease [ 48].