Sentence examples for enabling receptor from inspiring English sources
PET and SPECT have been proven to be particularly valuable for imaging targets in the central nervous system, enabling receptor occupancy measurements and dose selection for clinical candidates.
We have found that a proportion of NMDARs located in dendritic shafts, but not spines, are bound to glutamate under resting conditions, enabling receptor activation by bAPs.
A wide spectrum of functional peptides has been incorporated to different types of nanoparticles for the delivery of conventional drugs and nucleic acids, enabling receptor-specific cell binding and internalization, endosomal escape, cytosolic trafficking, nuclear targeting and DNA condensation.
In summary, Hi strains primarily require Ile-91 to enable receptor targeting.
The QTracker system uses a proprietary peptide targeting molecule, attached to the dot surface to enable receptor mediated endocytosis.
The Trojan horse enables receptor-mediated delivery of the fusion protein across the BBB so that the protein drug can enter the brain and exert the desired pharmacological effect.
In the present study, GDNF was re-engineered to enable receptor-mediated transport across the BBB following fusion of GDNF to the heavy chain of a chimeric monoclonal antibody (MAb) against the mouse transferrin receptor (TfR), and this fusion protein is designated cTfRMAb-GDNF.
Haubner and coworkers developed the first αvβ3-specific PET tracer [F]Galacto-RGD [ 8], a glycosylated cyclic pentapeptide, which demonstrated that PET with [F]Galacto-RGD enables receptor-specific monitoring of αvβ3 expression in murine tumour models.
Since the exposure of roach to fenitrothion was chronic, this may represent an adaptive cellular response to the continued inhibition of the androgen receptor, ultimately enabling androgen receptor-mediated activity even in the presence of the antiandrogenic effects of fenitrothion.
Receptor downregulation and desensitization increase the filter bandwidth thereby enabling the receptor systems to decode inputs in a wider frequency range.
Thus, the different residues within receptor binding site of the H2 HA appear to confer a selective advantage by enabling a receptor specificity switch allowing for transmission of a variant virus.
