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Synthego claims that by offering researchers one-click access to engineered cells with guaranteed edits in their desired target, the company can slash the time it takes to conduct experiments by months, enabling predictable and rapid outcomes in cell and gene therapy research and development. .
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Liu, C.C. et al. An adaptor from translational to transcriptional control enables predictable assembly of complex regulation.
The paper is titled "An adaptor from translational to transcriptional control enables predictable assembly of complex regulation.
Qi, L., Haurwitz, R.E., Shao, W., Doudna, J.A. & Arkin, A.P. RNA processing enables predictable programming of gene expression.
RNA processing enables predictable programming of gene expression NATURE BIOTECHNOLOGY Qi, L., Haurwitz, R. E., Shao, W., Doudna, J. A., Arkin, A. P. 2012; 30 (10): 1002-?
Recently, a set of engineered RNA controllers was described that enabled predictable tuning of gene expression in the yeast Saccharomyces cerevisiae through directed cleavage of transcripts by an RNase III enzyme, Rnt1p.
An adaptor from translational to transcriptional control enables predictable assembly of complex regulation NATURE METHODS Liu, C. C., Qi, L., Lucks, J. B., Segall-Shapiro, T. H., Wang, D., Mutalik, V. K., Arkin, A. P. 2012; 9 (11): 1088-?
The avoidance of cement precludes cement-related periimplant complications, while the elimination of occlusal screw access holes may enable predictable control over occlusion and improve the structural integrity of the prosthesis.
The application of computer-designed surgical templates enables predictable implant placement in oligodontia, where bone quantity and limited interdental spaces can be challenging for implant placement.
In our clinical practice, we take measures to prevent premature consolidation: first, we start distraction on the third day after surgery; secondly, we use cut olive wires inserted into the bone segments adjacent to the osteotomy to enable predictable distraction through the osteotomy instead of distraction of adjacent joints.
Synthetic biology [1], [2], [3], [4], [5], [6] seeks to enable predictable engineering of cells and biological systems with altered or expanded function.
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