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Transcription activator-like effector (TALE) proteins present a powerful tool for genome editing and engineering, enabling introduction of site-specific mutations, gene knockouts or regulation of the transcription levels of selected genes.
Gene flow has occurred to and from other such populations enabling introduction of new adaptive variation and potentially both enhancing and limiting local adaptation, depending on local selection regimes and migration-drift-selection equilibrium [ 24, 25].
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This capability would enable introduction of a Europe-wide road pricing system, on a miles travelled basis, which the EU Transport Commissioner is keen to introduce.
This intermediate enabled introduction of an amino group at C12 stereospecifically and in high yield.
Therefore, alternative vaccine delivery systems, which enable introduction of nonreplicating antigen into the MHC class I presentation pathway, are sought.
Other designs concern institutive and terminative rules; IAD rules of power that enable introduction, change and termination of such an instantiation e.g.g
The 3-N-linked 4-mercaptobutyrate auxiliary is readily synthesized in a single step and enables introduction on solid phase by means of reductive amination.
It has taken almost twenty-five years from the first research reports of the polymerase chain reaction [25] until recent regulatory clearances have enabled introduction specific PCR- and RT-PCR-based diagnostic assays and instrumentation into clinical practice.
Lowercase letters: deviations from the original OsRpl6-1 sequence to enable introduction of restriction sites.
ES cell-based targeting technology enables introduction of subtle genomic modifications, but it is a lengthy process involving multiple steps (reviewed by Menke 2013).
The absence of any paternal or zygotic effects enabled introduction of enhancer lacZ reporters into the atlas (see Materials and Methods; supplementary material Table S1).
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