Exact(24)
More generally, network architecture reflects cellular localization, biological process, and molecular function, enabling functional characterization of thousands of proteins.
Nonetheless, progress is hampered by a dearth of genome-wide tools enabling functional genomics.
Bioengineering of native-like multiscale building blocks provides refined control over the cellular microenvironment, thus enabling functional tissues.
Animal models help to elucidate the biological significance of such disease-associated DNA sequence variation by enabling functional relationships between disease genotypes and phenotypes to be defined.
By enabling functional diversification and optimization in the absence of detailed mechanistic understanding, directed evolution is a powerful complement to 'rational' engineering approaches.
Our data indicate that the Shh TAD promotes distance-independent contacts between distant regions that would otherwise interact only sporadically, enabling functional communication between them.
Similar(36)
All of these provide an initial estimation of gene function and enable functional genomics.
Hence, the cerebral plasticity may enable functional outcome after such procedures to some extent, particularly for motor function.
It also enables functional discriminant analysis through posterior predictive calculation.
Although these current methods have enabled functional characterization of regulatory variants at some GWAS loci, the progress is extremely slow.
These so-called soft modes, primarily driven by entropic effects, facilitate, if not enable, functional interactions.
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