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This method enables to define a discrete divergence operator leading to the respect of the Geometric Conservation Law GCLL).
The utilization of the ring RPS enables to define a scalar "tuning knob" for control behavior as well as the robustness of resulting controllers.
It enables to define a data structure (e.g. database table) interactively.
Therefore, the non-random nature of our amplification method enables to define a quality control assay consisting of four specific Mse I fragments that assess (i) whether a cell has been successfully isolated (small fragment) and (ii) whether the DNA has been fragmented prior to Mse I digestion (larger QC fragments from the QC1 assay).
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ROC curve analysis enabled to define a TI cut-off = 10.96 (Se 50% + Sp 74%).
Such transformations, which consist in a change of the time variable, enable to define a new time-scale denoted τ in which the control problem becomes unconstrained and is therefore simplified.
The groups are clusterized according to common keywords, enabling to define a p-value of the occurrence of the keyword in a specific group of genes inside the set of genes submitted, compared with the total gene content.
Since random groups of genes are also able to generate enrichments, a simulation was performed with random groups of genes which enabled to define a threshold for significance, as previously described [26].
This will enable to define a specific cognitive dysfunction pattern depending on these subtypes of depression.
This procedure was repeated thousand times, enabling to define a probability of random occurrence of a given pair (mean and coefficient of variation).
Phosphorylated PP2A is an alteration that determines poor outcome in metastatic CRC and represents a novel potential therapeutic target in this disease, thus enabling to define a subgroup of patients who could benefit from future treatments based on PP2A activators.
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