Sentence examples for enables the activation of from inspiring English sources

These results showed that the synthetic ZFP-TF can affect multiple genes simultaneously and enables the activation of gene.

Based on the enzymatic etching of CdS QDs enables the activation of quenching the charge transfer efficiency, thus leading to sensitive PEC recording of H2O2 level in buffer and cellular environments.

Upon LPS stimulation, CD14 enables the activation of the TLR4-TRAM-TRIF pathway and leads to the activation of NFAT transcription factor family members [ 29].

It can therefore be speculated that ER/IGF1-R crosstaleadsads to the induction of SCD-1 via mTOR signaling, which in turn enables the activation of signaling cascades associated with cell proliferation.

In contrast, the fibrin-bound plasminogen activator complex is much more resistant (approx. 100 fold) to α2-antiplasmin-mediated inhibition which enables the activation of plasminogen on the thrombus surface without the systemic fibrinolytic activation [ 10].

Inhibition of PP2Cs enables the activation of SNF1-RELATED KINASES 2 (SnRK2s) (Fujii et al., 2009; Umezawa et al., 2009; Vlad et al., 2009), that target transcription factors, ion channels and NADPH oxidases (Kobayashi et al., 2005; Furihata et al., 2006; Geiger et al., 2009; Lee et al., 2009; Sato et al., 2009; Sirichandra et al., 2009, 2010; Brandt et al., 2012).

Upon apoptosis induction, IAP proteins are antagonized by their endogenous inhibitor Smac (second mitochondria-derived activator of caspase), which is released from the mitochondrial intermembrane space, enabling the activation of caspases.

Density Functional Theory simulations conducted on In2O3(1 1 1), which was experimentally and theoretically shown to be the most exposed surface termination, indicated that oxygen vacancies surrounded by three indium atoms enable the activation of CO2 and split hydrogen heterolytically, stabilizing the polarized species formed.

Altogether, our data demonstrate that zVAD-fmk cannot potently prevent caspase-10 processing in Fas signalling, enabling the activation of a caspase-10-dependent alternative cytotoxic signalling pathway in response to FasL.

Engagement of PKC with the membrane leads to a conformational change and full activation of PKC, enabling the activation of PKC-mediated downstream signalling events.

Signaling complexity is increased further by receptor promiscuity, enabling the activation of different G proteins by the same receptor subtype.