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The precise identification of the site of biochemical recurrence of prostate cancer is important as it enables initiation of curative treatments such as radiotherapy and surgery.
The nucleation size which is three times smaller than the patch size in length enables initiation of earthquakes by compact acceleration, the size of which is approximately R c (nucleation), rather than by coalescence of creeping fronts (Chen and Lapusta 2009; Kaneko and Ampuero 2011).
Upon ligand binding, the GC receptor translocates into the nucleus where it enables initiation (transactivation) or suppression (transrepression) of target gene transcription.
Pol II with increased catalytic activity enables initiation earlier within the scanning window, increasing catalytic efficiency (initiation probability) of earlier usable start sites usages, and shifting TSS usage distribution upstream.
While we cannot completely rule out a role for physical pressure or additional contribution from a specific factor for activation, our data supports a model where an increase in Ca2+ due to osmotic swelling enables initiation of activation.
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For instance, proteins which enable initiation of the gene transcription to mRNA (so-called transcription factors) can be considered as input signals.
The presented case shows that Mendeliome sequencing can be applied in case of neonatal lactic acidosis, providing the diagnosis and thereby enabling initiation of treatment.
This is expected to improve patient prognosis by enabling initiation of treatment prior to loss of neuronal function (and associated cognitive decline), and can be used to support development of disease modifying therapeutics.
For in vitro transcription a T7 promoter-extended PCR product was generated, enabling initiation of T7-polymerase.
IIPCS enable initiation of HAI without laparatomy, and available data suggest favorable complication and failure rates.
IIPCS enable initiation of HAI without laparatomy, and are associated with favourable complication and failure rates [ 20- 22].
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