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The notion that a T3E repertoire enables a pathological convergence on a particular host implies that it is the coordinated action of several T3Es rather than the action of one unique T3E that matters.
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Two hypotheses can be formulated to explain host specificity: either it can be explained by the phylogenetic position of the strains, or by the association of virulence genes enabling a pathological convergence of phylogenically distant strains.
Advancement in DPRIA has enabled a refined pathological approach to determine immune cell densities and their distribution accurately throughout tumour, stroma and non-neoplastic tissue, yielding an average immune cell infiltration score across whole sections for distinct regions of interest.
The physical proximity of the ER to mitochondria enables a direct, selective transmission of physiological and pathological Ca2+ signals [ 1], an aspect highly variable between cell types.
Paper enables a certain kind of thinking.
Understanding how changes in the embryonic program for the production of additional segments of the body (somites) that form cartilage, muscle and bone are brought about in eels could enable a better understanding of pathological changes that affect these structures in a variety of human disorders and diseases.
This method enables an effective and high-throughput coverage of the metabolic changes involving the sphingolipidome during physiological or pathological states.
However, the amount of material obtained is occasionally insufficient to enable a discriminating diagnosis of primary and secondary lung cancers based on pathological findings.
Successful delineation of the genotypes would enable a more precise estimation of trichomonas species richness and permit a better epidemiological understanding of the pathological basis of these diseases.
The resected specimen was pinned on a Styrofoam plate by the surgeon, enabling accurate pathological assessment of the marked Clinical Tumor Volume and Gross Tumor Volume areas in patients treated with nCRT.
In UK, all patients diagnosed with molar pregnancies are registered in one of the three centres (Dundee for Scotland, Sheffield for Northern England and London for the rest of the UK) to enable centralised pathological review and surveillance using serial human chorionic gonadotrophin (hCG) measurements according to an established protocol (Seckl et al, 2010).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com