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This extended functionality enabled the prediction of a fatal human-specific hepatotoxicity caused by fialuridine (FIAU), which had escaped detection by preclinical models and short-term clinical studies.
Current in vitro in vivo correlation (IVIVC) enabled the prediction of pharmacokinetic profile of bufalin from in vitro permeation results.
The in vitro in vivo correlation enabled the prediction of pharmacokinetic profile of Lop from in vitro permeation results.
In addition, temperature distributions of the thermal energy during laser surface treatment enabled the prediction of various phase changes.
Current in vitro in vivo correlation (IVIVC) enabled the prediction of pharmacokinetic profile of MTZ from in vitro permeation results.
The model enabled the prediction of processing parameters in the feed and main extruders, from which the optimum conditions for processing TPNR were obtained.
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The identification of predictive cellular indicators for stress adaptive behavior will enable the prediction of the impact of adaptive responses during mild stress (processing) conditions on subsequent microbial robustness, and can be exploited to control these stress adaptive traits.
Models of different levels of physical complexity enable the prediction of avalanche motion.
This approach is enabling the prediction of delamination propagation without pre-allocating damage zones.
This model enables the prediction of induction times, improving working and safety conditions.
Applications of this model enable the prediction of the mechanical behavior of metals under various nonuniform deformations.
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