Verdier et al. [110] developed an HPLC assay method specifically targeting the needs of routine TDM application, thus enabling simultaneous determination of 12 beta-lactams within 22 minutes.
The resulting mixed-integer nonlinear program enables simultaneous determination of values of key decision variables including number of column trays, feed tray location of column, volume of reactor, process flowrates etc.
The sensor enables simultaneous determination of AA, DA and UA with linear responses from 0.3 to 285, 0.08 to 200, and 0.1 to 450 μM, respectively, and with 120, 30 and 30 nM detection limits (at an S/N of 3).
Verdier et al. [ 110] developed an HPLC assay method specifically targeting the needs of routine TDM application, thus enabling simultaneous determination of 12 beta-lactams within 22 minutes.
The method described enables simultaneous determination of 26 compounds with low detection limits (sub-μg L−1) and excellent precision, especially for highly halogenated solvents.
To determine transgene expression levels in cell pools as well as at the single cell level, the dual reporter gene lmg*[ 31] was employed, enabling simultaneous determination of luciferase activity and eGFP fluorescence.
Experimental results showed the immunoassay enabled the simultaneous determination of AFP and CEA in a single run with dynamic ranges of 0.01-50 ng mL−1.
Experimental results showed the immunoassay enabled the simultaneous determination of AFP and CEA in a single run with wide dynamic ranges of 0.001 5 ng mL−1.
