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Here we show that Zyx102 and Enabled (Ena), the Drosophila member of the Ena/VASP family, can interact specifically in vitro and that this interaction does not occur when a particular mutant form of Ena, encoded by the lethal ena210 allele, is used.
One of the interesting candidates showing progressive arrhythmicity has reduced enabled (ena) levels.
The enabled (ena) gene encodes the only Drosophila homologue of this family.
Enabled (Ena) is an actin-polymerizing factor that genetically antagonizes the Abl tyrosine kinase (reviewed by [54]).
Plasmid rescue analysis revealed that P[UAS]117 is inserted within the first exon of enabled (ena) upstream of the ATG, and thus it interrupts four out of the five splice variants predicted (Fig. 3A).
It has been proposed, in fibroblasts, that filopodia formation from lamellipodia is a tightly regulated process which is partly controlled by actin binding proteins such as enabled (Ena) / vasodilator-stimulated phosphoprotein (VASP) capping the actin filament [38].
We identified the candidate effector protein Enabled (Ena), a founding member of the highly conserved Ena/VASP (Vasodilator-Stimulated Phosphoprotein) protein family.
First data about Mena (mammalian Ena homolog) protein, a relative of VASP (vasodilator stimulated phosphoprotein) and Drosophila protein enabled (Ena), were published in 1996 by Gertler et al. [ 1].
Nevertheless the assay enabled us to obtain interesting results.
The verified luminaire model was further investigated with multi-domain models of aged LEDs obtained during an LM-80 standard compliant aging of a set of LEDs, characterizing LEDs up to 6000 + h of operating life time.
It was Brown's large expiring contract that enabled the Lakers to obtain Gasol from Memphis.
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