Quartz crystal microbalance with dissipation (QCM-D) monitoring enabled label-free detection of full-length NS5B membrane association, its interaction with replicase subunits NS3, NS5A, and template RNA, and most importantly its RNA synthesis activity.
This enabled labels to invest more heavily in new talent – Campkin suggests that Britpop might not have happened without the CD windfall – but it also funded misguided A&R frenzies, wasteful marketing and excessive pay packets.
This enabled labeling and preclinical application as previously shown with 44Sc (Domnanich et al. 2016).
The Sel-tag enabled labeling at the same site with fluorescent and radioactive labels, which allowed evaluations of the tracers' EGFR binding capabilities in vitro, ex vivo, and in vivo.
Consequently, recent developments that have enabled label-free peptide and protein quantification have attracted much attention.
Nanopore sensing has enabled label-free single-molecule measurements on a wide variety of analytes, including DNA, RNA, and protein complexes.
Metabolic labelling techniques for MS based quantitative proteomics enable labelled and unlabelled samples to be combined at the tissue level.
It enables label-free identification of cellular metabolic changes with high sensitivity and has already been successful applied to 2D and 3D cell cultures.
In this paper we present a modification to the popular two-scan CCL algorithm that enables labeling of giga-cell size, multi-categorical rasters.
Multiphoton microscopy enables label-free immediate visualization of many biological processes in living tissue at subcellular resolution.We used multiphoton microscopy to study the different developmental stages of spermatogenesis using neonatal, pubertal and adult rat testes.
The synthesized compounds have chemical features that could enable labeling with a positron emitter radioisotope (carbon-11 or fluorine-18) and lipophilicity within the range considered optimal for brain penetration and low non-specific binding.
