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For instance, selective labelling of the methylating agent temozolomide in the carbonyl and methyl positions has enabled demonstration of the ring-opening of this compound in man (Saleem et al, 2001b).
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The Department of Housing and Urban Development issued guidelines in April 1999 to enable demonstration programs to get under way.
A solar reactor model of a special design was developed in order to enable demonstration of the effectiveness of the proposed method.
On the other hand, vaccination of 8303 Estonian hrHPV negative women among the entire 15-year-old female birth cohort (about 10 000 women) with an already licensed HPV vaccine would enable demonstration of 70% VE against ICC by 20 years of registry follow-up of these and comparable 16 606 women identified among the 16 19-year-old 16 19-year-old 16 19-year-old
A low-dose active comparator design was therefore developed to enable demonstration of clinical efficacy of a new drug using a superiority design [ 25].
This study will enable demonstration of a complete health system perspective of the impact of rotavirus vaccination on the burden of disease in Merseyside, UK.
A larger number of cancers in our middle and older group may provide more statistical power to enable demonstration of better performance as compared to the younger group.
Alternative approaches include intravenous injection of purified antibody [ 31], but this would only enable demonstration of renal deposition and not pathogenicity, unless repeated injections were given over a period of several days to weeks.
Taken together, these conclusions lead to the recommendations that any future progression of FAAH inhibitors for human disease should be accompanied by efforts to develop technologies that will enable demonstration of pharmacology at CB1, as advocated more generally by others.
Donors homozygous for the 131R allotype of FcγRIIa, which binds murine IgG1, were used to enable demonstration of efficient blocking of FcγRIIa by IV.3 Fab: the CL response to a murine IgG1 CD41Ab was inhibited by 98%.
This example nicely illustrates the benefit of complete characterization since it enables demonstration of the association of a loss of magnetic properties with the biotransformation of the material into poorly magnetic species (rather than a disappearance of the material).
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CEO of Professional Science Editing for Scientists @ prosciediting.com