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The modulation of α0 corresponds to the signal-response relationship enabled by the underlying chemotaxis pathway.
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Further progress in the search for dosage-sensitive genes underlying DS has been enabled by the generation of several mouse models of DS.
Of note, the models are not strictly tied to a single target or therapeutic class, and can be extended quickly by the addition of physiologic or cellular components of interest, as demonstrated here for LSBMD, and enabled by incorporation into the underlying bone and calcium homeostasis MSPM.
The natural color of a permanent tooth is determined by the enamel translucency enabling the underlying dentine color to be visible.
Systems biology approaches hold the promise of substantially improving the current state-of-the-art in medicine by clarifying distinctions between multiple disease states and enabling the underlying molecular causes of a disease to be identified [ 6- 8].
Anything over 17 years is affected by the underlying trend.
This is enabled by exploiting the special graph structure described in Section 3. The underlying principle of this exploitation is the fixed-parameter tractability (FPT) of the problem.
This enables the sequence underlying the successive stages of research and/or policymaking to be preserved.
Moreover, our approach will enable better understanding of the underlying biology of disease by observing the patterns of association between gene expression and clinical parameters at multiple gene set levels.
Modelling this progression enables us to identify the underlying trends and behaviours in sports and history on a world scale.
The direct targeting of underlying causes enabled by this method can provide dramatic improvement in the unburned carbon in fly ash (carbon-in-ash or CIA), improving the commercial value of the ash as an additive in the production of concrete and cement and improving boiler efficiency.
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