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We now know of many different actions: p53 controls DNA repair and natural cell death; RB regulates the cell cycle; APC enables cell-to-cell recognition.
In addition to demonstrating a physiological role for ECM-induced CDC42 activation in sprouting angiogenesis, our work has therefore identified a mechanism that ensures the integration of growth factor signals with ECM cues via NRP1 to enable tip cell function in sprouting angiogenesis.
Such 'σ cross regulation' might enable the cell to integrate signals transmitted via σ and an alternative σ factor to modulate gene expression within a single transcription unit under the control of a non σ dependent promoter.
These results suggest that rapid mechanical stimulus transmission in cells is only enabled via transverse stress fiber motion.
LightSurf has developed software to enable a cell phone attached to a tiny camera to send pictures via the wireless Web.
In this CoMP system, cooperation is enabled for cell-edge users via dynamic switching between the normal single-cell operation and CoMP.
Residual killing activity is probably enabled via NKp44.
Programmatic data access is enabled via SOAP web services.
Our previous studies showed that overexpression of human Dsg3 in cancer cell lines causes dissolution of both classical and desmosomal cadherins via Src activation.8, 10 However, to enable tumor cells to invade into the neighboring tissues, additional properties that involve multigenic processes and coordinated rearrangements of the actin cytoskeleton are required.
This is in agreement with formation of extracellular glycoside hydrolases and enabled to follow growth via cell density measurements.
A perfluorocarbon particle loaded cell scheme has been used to show the unequivocal and unique signature for SC, enabling spatial cell localization viaF- MRI and quantitation via F-spectroscopy [ 56].
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