Exact(3)
Expression arrays enable us to interrogate the transcription level of all known genes in a single hybridization experiment.
This allele may thus enable us to interrogate the role of BAF57 in a way not feasible with any BAF57 null allele, whether the null is constitutive or conditional.
The new knowledge allowing genomics to inform disease and treatment disparities across ethnic and continental ancestry populations stems directly from improvements in technology, tools, and methods from the Human Genome Project and related projects that enable us to interrogate the genome in a broad, flexible, and affordable way.
Similar(57)
The underlying acyl transfer reactions with sulfur and selenium provide an efficient means to synthesize, remodel, and immobilize proteins, and they have enabled us to interrogate biological systems.
gambiae [ 35], together with technological advances in small RNA cloning methods, enabled us to interrogate the miRNA repertoire in two flavivirus mosquito vectors.
Recent advances in both mosquito genomics and high-throughput sequencing technologies enabled us to interrogate the miRNA profile in these two species.
With sequencing costs dropping rapidly, we will be soon shift from analysis of exomes to genomes, enabling us to interrogate many more variants that might be important for controlling gene transcription, splicing or even translation.
The development of a serum-free protocol to generate "fully licensed" DC in vitro [ 18] and the identification of an immunogenic CDR3 peptide of the A20 Id enabled us to interrogate the possible extremes in Id vaccination, i.e. to analyze responses to a unique CDR3 peptide versus a FR4/J peptide expressed by many normal B cells.
Rpn13−/− mice showed only reduced viability and close to 60% of the surviving pups reached adulthood, which enabled us to further interrogate the in vivo function of this proteasomal receptor.
Future improvements in imaging should enable us to generate large libraries of digital mouse embryos from fertilisation to implantation that can be interrogated for quantitative information and population behaviour.
We hypothesized that treatment with MK-2206 in cells ectopically expressing drug resistant Akt isoforms will enable us to acutely block endogenous Akt activity and thereby restrict insulin signalling to the drug resistant, transgenic Akt isoform, providing a cellular system to interrogate isoform specific Akt signalling.
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