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Second, the cut-off frequency ω0 should be high enough to enable the pathway to response to fast-changing ligand concentration.
Theme A: Ownership of the pathway by the whole cancer services team was the central theme of the study, to enable the pathway to be acceptable to everyone participating in its delivery.
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Within the United Kingdom, a potential solution is the National Cancer Data Repository (NCDR) (National Cancer Intelligence Network, 2012) that contains population-based routine administrative National Health Service (NHS) data sets linked together to enable the pathways of all diagnosed with cancer in England to be tracked from diagnosis to cure or death.
Some centers do offer early neurosurgical opinion so patients are more aware of the options open to them and it enables the pathway to be accessed quicker in an emergency [ 28].
Cell-to-cell contact is critical for the activation of Notch signaling, which subsequently enables the pathway to modulate genes involved in cell fate such as proliferation or differentiation [ 11].
Our approach not only enables the pathways associated with disease to be identified, but provides a method to identify the individual genes and their SNPs within the pathway that are predominantly responsible for the genetic effect.
The typical features of porous materials enable the long diffusion pathway and relatively low power density.
We propose that the clap-net like design of the stacked-graphene could enable the effective conducting pathway for electron transport, while protecting the active material inside.
Bacterial cell-wall peptidoglycan biosynthesis is a well-established target for antibacterial chemotherapy, and recent developments enable the entire biosynthetic pathway to be reconstituted for detailed biochemical study and high-throughput inhibitor screening.
For databases of pathway/gene set network, Sudhir, et al. developed Human Pathway Database HPDD) to enable the study of human pathway networks [ 8].
This will enable the identification of possible pathways for clinical intervention while pointing to putative biomarkers for early diagnosis of these disorders.
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