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Cell-based RNA interference (RNAi) screens enable the inference of large numbers of genes that regulate signaling pathways, but these screens cannot provide network structure directly.
In this work, we demonstrate that such identical-by-descent (IBD) segments are informative about a number of relevant population genetics features: they enable the inference of details about past population size fluctuations, migration events, and they carry the genomic signature of natural selection.
Both formal languages extend RDF and enable the inference of new knowledge.
TILAR was extended to enable the inference of gene regulatory networks from time resolved data by a system of differential equations approximated by a set of difference equations with the time interval Δt= t m − t m −1.
Scientific findings, even if they exclusively include qualitative information about specific observations, have to rely in some form on quantitative measurements that enable the inference of the reported qualitative information.
The above stated advantages of the NMF method however, come with the need of having enough diversity in data such that the simplex formed by the data vectors is filled adequately to enable the inference of the underlying simplex structure.
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Parallel analysis of the nuclear phosphoproteome enabled the inference of the temporal activity of kinases accounting for rhythmic phosphorylation.
Missing data were estimated using Beagle v3.3, which enables the inference of haplotypes and imputation of sporadic missing data in large-scale genotype datasets (Courtois et al. 2013).
ChemDIS utilizing chemical protein interactions from the large database STITCH 4 enables the inference of potential risks for a wide range of chemicals.
Alignment of a sequence to gene regions with known transcripts also enabled the inference of sequence orientation.
The model developed here is strictly dynamical, describing the growth of two interacting populations (species), but it enables the inference of evolution by a couple of devices.
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