It enables the first step of metastasis – local invasion and dissemination of cancer cells from the primary tumour.
The MMPs have a crucial role in all of these processes, MMP-1 enabling the first step of fibrillar collagen cleavage, after which other MMPs, including MMP-2 and MMP-9, further degrade collagen fragments [ 30].
This has enabled the first steps in a shift from the use of cytotoxic drugs to highly selective targeted therapeutic agents for the treatment of cancer.
The R&D budgets grew and this, alongside advancements in the underlying smartphone technology, enabled the first steps toward true mobile augmented reality: The software began to understand what it could see.
They enabled the first steps of my becoming a software engineer.
Recent availability of rust pathogen genome sequences has enabled the first steps towards wide-scale cataloguing of putative effector proteins.
We believe that the SADI web services, the semantic resource envelopment, and the seamless machine reasoning they enable constitute the first step on our journey to a way of practicing science that transcends disciplines, knows no barriers, and encompasses all human knowledge without taxing the beholder with menial and irrelevant tasks: a self-aware science.
On the other hand, as already mentioned, hypertension is also associated with lack of vitamin D, due to activation of the RAA system, enabling endothelial dysfunction, the first step in plaque formation.
Inanimate objects with cameras enable companies to own the first step in gathering the data for computer vision and artificial intelligence algorithms to analyze.
As the first step enabling the SUs sharing the spectrum with the PU, the spectrum sensing component needs to reliably and autonomously identify unused frequency bands.
