Sentence examples for enable the disruption of from inspiring English sources

These Cas9-based gene-editing techniques will enable the disruption of a wide variety of target genes, including endogenous TCR, the checkpoint receptors PD1 or CTLA-4 in tumour-targeting T cells or the virally targeted chemokine receptors CCR5 and CXCR4 in T cells of HIV patients.

Speaking in Baltimore the next week, Alexander gave an exact figure: 54 cases "in which these programs contributed to our understanding, and in many cases, helped enable the disruption of terrorist plots in the U.S. and in over 20 countries throughout the world".

Since most tumours become refractory to current hormonal therapies within a year of starting treatment, FKBPL represents a novel drug target that would enable the disruption of signalling pathways integral in maintaining ER-mediated tumour growth and survival.

For those who might be wondering what PCH would bring to your fledgling product or startup, PCH as a business has enabled the disruption of traditional supply chain models, contributing to the success of many of the world's largest technology brands.

A chart declassified by the agency in July, for example, says that intelligence from the programs on 54 occasions "has contributed to the [U.S. government's] understanding of terrorism activities and, in many cases, has enabled the disruption of potential terrorist events at home and abroad" — a much different claim than asserting that the programs have been responsible for thwarting 54 attacks.

Moreover, genetic modification techniques have enabled the disruption and 'rewiring' of metabolic fluxes to improve the production of target products (Atsumi et al., 2008; Becker et al., 2011).

Bain Capital, for example, says it will invest $2 million to $5 million per year to sponsor Angel Fund deal leads, in effect "acknowledging, participating in and enabling the gradual disruption of the venture capital industry," says managing director Salil Deshpande, who will lead the program on behalf of his firm.

The markerless retrotransposition strategy enabled the rapid disruption of Ccel_2485 and Ccel_0137 genes in C. cellulolyticum, and their combination resulted in a strain that produced remarkably high yields of ethanol during polysaccharide and switchgrass fermentations.

The researchers say the new type of imaging - which tracks the movement of water in the brain - will enable them to explore how the disruption of key processes might cause conditions such as autism.

Phosphorylation at the Ser position enables its association with FADD, leading to the disruption of the DISC assembly and blocking apoptosis [ 21].

Disruption of tumour angiogenesis has been extensively investigated to enable the development of novel anti-tumour strategies.